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Chung-Shan Yu Selected Research

fenbufen

12/2017Dataset on the synthesis and characterization of boron fenbufen and its F-18 labeled homolog.
9/2017Synthesis and characterization of boron fenbufen and its F-18 labeled homolog for boron neutron capture therapy of COX-2 overexpressed cholangiocarcinoma.
3/2016Synthesis and Biological Evaluation of an (18)Fluorine-Labeled COX Inhibitor--[(18)F]Fluorooctyl Fenbufen Amide--For Imaging of Brain Tumors.
4/2013[123I]Iodooctyl fenbufen amide as a SPECT tracer for imaging tumors that over-express COX enzymes.
3/2011Solution-phase parallel synthesis and screening of anti-tumor activities from fenbufen and ethacrynic acid libraries.

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Chung-Shan Yu Research Topics

Disease

9Neoplasms (Cancer)
04/2020 - 04/2006
6Cholangiocarcinoma
12/2017 - 06/2012
4Brain Neoplasms (Brain Tumor)
04/2020 - 01/2014
1Liver Neoplasms (Liver Cancer)
09/2017
1Glioma (Gliomas)
01/2015
1Nervous System Diseases (Neurological Disorders)
01/2014
1Herpes Simplex
04/2012
1Fibrosarcoma
04/2012
1Prostatic Neoplasms (Prostate Cancer)
01/2008

Drug/Important Bio-Agent (IBA)

5fenbufenIBA
12/2017 - 03/2011
5AmidesIBA
03/2016 - 03/2011
3BoronIBA
04/2020 - 09/2017
3EnzymesIBA
09/2017 - 04/2013
2Celecoxib (Celebrex)FDA Link
01/2018 - 01/2013
2Thioacetamide (Thioacetamid)IBA
04/2013 - 06/2012
2Thymidine KinaseIBA
01/2008 - 04/2006
1Boron-10IBA
04/2020
1Tryptophan (L-Tryptophan)FDA Link
04/2020
1Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
01/2018
1Glucose (Dextrose)FDA LinkGeneric
09/2017
1HeliumIBA
09/2017
1Biological ProductsIBA
03/2016
1DNA (Deoxyribonucleic Acid)IBA
01/2015
1Biomarkers (Surrogate Marker)IBA
01/2015
1Reactive Oxygen Species (Oxygen Radicals)IBA
01/2015
1prostaglandin R2 D-isomerase (prostaglandin D2 synthase)IBA
01/2014
1Glutathione (Reduced Glutathione)IBA
01/2014
1LipocalinsIBA
01/2014
1thymidine kinase 1IBA
04/2012
1alovudineIBA
04/2012
1Ethacrynic Acid (Etacrynic Acid)FDA Link
03/2011
1SolutionsIBA
03/2011
1Cisplatin (Platino)FDA LinkGeneric
03/2011
1BromidesIBA
03/2011
1thiazolyl blueIBA
01/2008

Therapy/Procedure

3Boron Neutron Capture Therapy
04/2020 - 09/2017
2Therapeutics
09/2017 - 09/2015